HPLC Columns and Cartridges
Mac-Mod MAC-MOD Chiral Amy-2, 3.0 µm, 3.0 mm x 100 mm HPLC Column, for Reversed-Phase Use
MAC-MOD Chiral HPLC, UHPLC and SFC Chiral Columns are an exciting range of Amylose or Cellulose coated Reversed-Phase or Normal Phase columns proud to be manufactured in the USA. These columns should be your first choice when scouting new selectivity options to improve resolution of racemic enantiomeric mixtures. These columns are also an excellent choice to compare with current Chiral column offerings to see if novel bonding and packing methods can improve resolution. MAC-MOD Chiral columns offer a wide range of novel chiral selectors as well as similar chiral selectors to industry standard chiral columns. However, all chemistries should be tried to ensure proper screening of chiral selectors due to proprietary silica manufacturing and packing mehtods that may still deliver increased resolution to industry standard comparisons.
Mac-Mod Princeton HILIC-ZIC 100 Å, 10 µm, 50 x 250 mm SFC Column
Princeton Chromatography Achiral SFC columns are designed and manufactured in the US, well known for innovating novel and robust workhorse phase chemistries, for the analysis of achiral SFC applications. Princeton designs myriad phase chemistries to improve the selectivity and efficiency of SFC analysis. Known for originally innovating the 2-EP phase chemistry, explore what Princeton has to offer. Columns are available from analytical to preparative sizes and are available in a wide range of pore sizes, particle sizes, column ID's and lengths. If you do not see something that you want, please just ask!
Mac-Mod Princeton Cyano (CN) 100 Å, 10 µm, 4 x 250 mm SFC Column
Princeton Chromatography Achiral SFC columns are designed and manufactured in the US, well known for innovating novel and robust workhorse phase chemistries, for the analysis of achiral SFC applications. Princeton designs myriad phase chemistries to improve the selectivity and efficiency of SFC analysis. Known for originally innovating the 2-EP phase chemistry, explore what Princeton has to offer. Columns are available from analytical to preparative sizes and are available in a wide range of pore sizes, particle sizes, column ID's and lengths. If you do not see something that you want, please just ask!
HELIX CHROMATOGRAPHY Amaze RP A1 4.6 x 150 mm, 3 um
Mixed-mode stationary phase combining reversed-phase, cation-exchange, and anion-exclusion mechanisms. Provides broad retention for amino acids, hydrophilic and hydrophobic compounds, inorganic cations, basic drugs, and anionic counter-ions. Offers strong retention for basic analytes under acidic conditions, making it suitable for challenging separations of protonated compounds. Functional groups are integrated on a single ligand. A strong acidic group (pKa ~1) is positioned in the inner layer of the stationary phase close to the silica surface, minimizing interaction with residual silanols and improving peak shape for basic analytes. Incorporates surface-bound ion-pairing functionality, enabling full MS compatibility without the need for mobile phase ion-pairing reagents. Provides comparable selectivity and retention to established mixed-mode stationary phases, enabling direct method transfer with minimal adjustment.
HELIX CHROMATOGRAPHY Amaze RP A1 4.6 x 150 mm, 5 um
Mixed-mode stationary phase combining reversed-phase, cation-exchange, and anion-exclusion mechanisms. Provides broad retention for amino acids, hydrophilic and hydrophobic compounds, inorganic cations, basic drugs, and anionic counter-ions. Offers strong retention for basic analytes under acidic conditions, making it suitable for challenging separations of protonated compounds. Functional groups are integrated on a single ligand. A strong acidic group (pKa ~1) is positioned in the inner layer of the stationary phase close to the silica surface, minimizing interaction with residual silanols and improving peak shape for basic analytes. Incorporates surface-bound ion-pairing functionality, enabling full MS compatibility without the need for mobile phase ion-pairing reagents. Provides comparable selectivity and retention to established mixed-mode stationary phases, enabling direct method transfer with minimal adjustment.
Mac-Mod Princeton HA-Dipyridyl 100 Å, 5 µm, 50 x 50 mm SFC Column
Princeton Chromatography Achiral SFC columns are designed and manufactured in the US, well known for innovating novel and robust workhorse phase chemistries, for the analysis of achiral SFC applications. Princeton designs myriad phase chemistries to improve the selectivity and efficiency of SFC analysis. Known for originally innovating the 2-EP phase chemistry, explore what Princeton has to offer. Columns are available from analytical to preparative sizes and are available in a wide range of pore sizes, particle sizes, column ID's and lengths. If you do not see something that you want, please just ask!
HELIX CHROMATOGRAPHY Amaze RP A2 4.6 x 150 mm, 3 um
Mixed-mode stationary phase combining reversed-phase, cation-exchange, and anion-exclusion mechanisms. Provides broad retention for amino acids, hydrophilic and hydrophobic compounds, inorganic cations, basic drugs, and anionic counter-ions. Offers balanced retention and selectivity for both strongly and moderately basic analytes, providing flexibility across a wide range of pH conditions. Functional groups are integrated on a single ligand. A medium strength acidic group (pKa ~2) is positioned in the inner layer of the stationary phase close to the silica surface, minimizing interaction with residual silanols and improving peak shape for basic analytes. Incorporates surface-bound ion-pairing functionality, enabling full MS compatibility without the need for mobile phase ion-pairing reagents. Provides comparable selectivity and retention to established mixed-mode stationary phases, enabling direct method transfer with minimal adjustment.
HELIX CHROMATOGRAPHY Amaze RP A3 2.1 x 100 mm, 3 um
Mixed-mode stationary phase combining reversed-phase, cation-exchange, and anion-exclusion mechanisms. Provides broad retention for amines, hydrophilic and hydrophobic compounds, inorganic cations, basic drugs, and anionic counter-ions. Provides moderate cation-exchange retention with enhanced selectivity for basic analytes, while proprietary ligand design introduces additional chelation interactions for unique separation behavior. Functional groups are integrated on a single ligand. A medium strength acidic group (pKa ~3) is positioned in the inner layer of the stationary phase close to the silica surface, minimizing interaction with residual silanols and improving peak shape for basic analytes. Incorporates surface-bound ion-pairing functionality, enabling full MS compatibility without the need for mobile phase ion-pairing reagents. Provides comparable selectivity and retention to established mixed-mode stationary phases, enabling direct method transfer with minimal adjustment.
Waters Corp XSelect HSS T3 Column, 100Å, 5 μm, 4.6 mm X 250 mm
The HSS T3 column is a fully endcapped, low-coverage C18 bonded-phase column designed to retain extremely polar compounds by reversed-phase in high aqueous mobile phases. It utilizes high strength silica technology, offering higher silanophilicity for increased polar compound retention and significantly different selectivity. This technology also provides the mechanical strength for UPLC pressures, supreme reproducibility, and seamless scalability. It facilitates higher resolution separations for complex samples, combining efficiency and selectivity.
- Fully endcapped, low-coverage C18 bonded-phase for specific retention.
- Designed to retain extremely polar compounds by reversed-phase in high aqueous mobile phases.
- Utilizes high strength silica technology.
- Possesses mechanical strength necessary for UPLC pressures.
Waters Corp Column, Atlantis Premier BEH C18 AX VanGuard FIT, 5 μm, 2.1 x 50 mm
The Atlantis Premier BEH C18 AX Columns provide excellent retention for polar acidic analytes with stable reversed-phase/anion-exchange mixed-mode chemistry (pH 2 to 10). The VanGuard FIT guard-column design reduces dead volume and increases column lifetime by preventing contaminants from reaching the analytical column.
- Retains polar acidic analytes under reversed-phase conditions.
- Stable reversed-phase/anion-exchange mixed-mode chemistry (pH 2 to 10).
- VanGuard FIT guard-column design reduces dead volume and extends column lifetime.
- Protects analytical column from contaminants like sample matrix and particles.
- Constructed with 5 μm particle size, 2.1 x 50 mm dimensions.
- Ideal for biological fluid cleanup and temperature-controlled applications.
- Operates at pH 10 max, 60°C max, and 18,000 psi (1240 Bar) max pressure.
Sepax Technologies Inc Sepax HPLC Column Zenix-C SEC-300, 3 µm, 7.8 x 300 mm
Zenix™-C SEC phase, developed based on innovative surface coating technology, comprises of uniform, hydrophilic, and neutral nanometer thick film chemically bonded to high purity and mechanically stabilized silica. Zenix™-C, uses lay-down monolayer on porous silica as oppose to Zenix of stand-up monolayer, offers ideal phase chemistry for hydrophobic samples like insulin, membrane protein monoclonal antibodies derivatized with polymer branches (polypeptide or PEG) separation. The 3µm based packing material allows for high resolution and performance separation.
Waters Corporation C4 Column, 300 Å, 5 μm
Symmetry columns are designed to provide confidence in the long-term compliance of HPLC methods. They ensure consistent peak shape, selectivity, column-to-column and batch-to-batch reproducibility, and other critical performance characteristics. This column primarily supports legacy methods.
- Features C4 chemistry and reversed phase separation mode
- Silica particle substrate with a spherical shape
- pH range of 2 to 8
- Maximum pressure of 6000 psi (415 Bar)
- Endcapped with low silanol activity
- Molecular weight range of 1000 to 30000
- Pore size of 300 Å and particle size of 5 μm
- Dimensions: 2.1 mm inner diameter and 150 mm length
- 2.8 % carbon load
- Suitable for protein applications
- One unit per package
Sepax Technologies Inc Sepax HPLC Column Zenix SEC-80, 3 µm, 2.1 x 300 mm
Made of 3 µm silica particles, Zenix SEC packing is a breakthrough technology for size exclusion chromatography. Combination of 3 µm silica particle size and proprietary surface technology enables highest separation efficiency and resolution for biological molecules and water soluble polymers. Available pore sizes of Zenix packings are 80, 100, 150 and 300 Å
Sepax Technologies Inc Sepax HPLC Column Bio-C8, 5 µm, 300 Å, 10 x 250 mm
Bio-C8 phase is made of monomeric and fully endcapped chemistry. The uniform stationary phase allows the separation to achieve high selectivity and high efficiency. Bio-C8 packings of 300 Å pore size selection are ideal for high resolution mapping of peptides and separation of natural and synthetic peptides and small proteins.
Waters Corp Waters Viridis Silica OBD Prep Column, 5 μm, 30 mm x 150 mm
Viridis Silica columns are engineered for high reproducibility and predictability, achieved through stringent product specifications and minimal metal content. They are suitable for both analytical screening and preparative purification, allowing optimization and scale-up of separation methods to preparative OBD columns.
- Spherical silica particles: 5 μm particle size, 0.9 cc/g pore volume, 100 Å pore size, and 340 m²/g surface area.
- High reproducibility and predictability from tight specifications and low metal content.
- Suitable for both analytical screening and preparative purification.
- Methods are scalable to preparative OBD columns.
- Good retention, peak shape, and selectivity in achiral SFC separations, with or without additives.